Finally, we are given a clear reason behind why Iggy has Skin specifically as his Guardian. This was hinted at extremely early on in the comic (back when Peter and Iggy first met during the first dozen strips of the series), but hasn't really been clearly explained until now. It turns out Iggy has a bit of a hyperactivity issue and Skin is there to keep him from hurting himself too badly.
Not everyone gets a Guardian simply because they are bullied or socially awkward. There are countless reasons why a child might need one, and each case is unique.